Smallpox Control by Mass Vaccination with Dried Vaccine

Smallpox Vaccination

This article was presented by the author at the Vaccination Seminar of May 26, 1972, National University Medical School.

Ring Vaccination and Smallpox Control

We present a stochastic model for the spread of smallpox after a small number of index cases are introduced into a susceptible population. The model describes a branching process for the spread of the infection and the effects of intervention measures. We discuss scenarios in which ring vaccination of direct contacts of infected persons is sufficient to contain an epidemic. Ring vaccination can...

Safety profile of smallpox vaccine: insights from the laboratory worker smallpox vaccination program.

BACKGROUND The frequency of mild-to-moderate adverse events following smallpox vaccination was not well documented or reported during the pre-eradication era. This report describes the frequency of such symptoms among 936 adult smallpox vaccinees with and without a history of prior smallpox vaccination. METHODS Diary cards were distributed to 1006 laboratory workers and members of the Centers...

Mass Smallpox Vaccination and Cardiac Deaths, New York City, 1947

In April 1947, during a smallpox outbreak in New York City (NYC), more than 6 million people were vaccinated. To determine whether vaccination increased cardiac death, we reviewed NYC death certificates for comparable periods in 1946, 1947, and 1948 (N = 81,529) and calculated adjusted relative death rates for the postvaccination period. No increases in cardiac deaths were observed.

A mass smallpox vaccination campaign: reasonable or irresponsible?